Two papers, supported in part by Cure Alzheimer’s Fund,  have just been published in two leading research journals. The findings show links between certain kinds of anesthesia and pathological features of Alzheimer’s disease. 

This Science Update gives you an overview about what is know about the science behind Alzheimer’s disease and how at Cure Alzheimer's Fund we are funding research to get to a cure as quickly as possible.

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Annual Awards Support “Tomorrow’s Leaders in Alzheimer’s Disease Research;”

Honor Legacies of Drs. George Glenner and Leon Thal

April 9, 2008 – A coalition of leading Alzheimer’s disease organizations today announced the first three recipients of “Tomorrow’s Leaders in Alzheimer’s Disease Research” prizes; a new award mechanism to recognize outstanding young scientists in Alzheimer’s and dementia research. 

Award winning, national-best selling author David Shenk takes a unique look at Alzheimer’s through a series of four very-short animated films aimed at increasing the understanding of Alzheimer's disease. Cure Alzheimer’s Fund Dr. Rudy Tanzi served in an advisory role to help produce these films. They can be accessed and downloaded at the Web site. The films are free for non-commercial use by anyone at anytime. 

By Charles Glabe, Ph.D. University of California at Irvine
Professor, Molecular Biology and Biochemistry, School of Biological Sciences.

The current treatments for AD target the disease symptoms and to prevent or cure AD, new treatments are needed that target the causes of the disease.  Aß oligomers are a leading candidate for causing AD, so it makes sense to develop strategies to prevent their formation, promote their elimination or inhibit their toxic activity.

The core research effort currently funded by Cure Alzheimer’s Fund is the Alzheimer's Genome Project™ initiative. This project, entirely funded by Cure Alzheimer’s Fund, is being led by Dr. Rudolph Tanzi at Massachusetts General Hospital. The objective is to identify all genes that contribute significant risk for Alzheimer’s disease, thereby identifying more targets for the development of therapeutic interventions.