Known Alzheimer's disease genes account for only 30% of genetic activity of the disease. With 70% of the genetic component of Alzheimer's unknown, not even the best efforts can develop effective therapies to slow, stop or reverse the disease. Cure Alzheimer's Fund is going to the heart of this problem with the Alzheimer's Genome Project Intiative.
 
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Sangram S. Sisodia, Ph.D. Print
Photo of Sangram S. Sisodia, PhD University of Chicago
Thomas A. Reynolds Sr. Family Professor of Neurosciences.

Dr. Sisodia is a leading expert on the molecular and cell biology of Alzheimer's disease pathology.  He has been at the forefront of learning how the familial Alzheimer's disease (FAD) genes, including the amyloid precursor protein and the presenilins, function normally, and contribute to Alzheimer's disease pathogenesis. Most recently, Dr. Sisodia's studies have shown that in mice, exercise has a remarkable ability to protect against Alzheimer's disease pathology by favorably changing gene activity in the brain.
 
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