Zhongcong Xie, MD, Ph.D.
Mass General Hospital/Harvard
Funded in 2011 for work on "Surgery-induced Brain Inflammation Interacting With Genetic Mutation-Induced Elevated A-beta, Leading to Memory Impairment"
Funded Research
Project Description Researchers Funding General Anesthetics and Alzheimer’s Disease The goal of this project is to test the hypothesis that desflurane is a safer anesthetic than isoflurane for AD patients in order to find safer anesthetics that won’t worsen AD symptoms.
Zhongcong Xie, MD, Ph.D. 2012
$100,000
Selected Publications
These published papers resulted from Cure Alzheimer’s Fund support.
, "Isoflurane-induced caspase-3 activation is dependent on cytosolic calcium and can be attenuated by memantine." , J Neurosci , 28 , April 23, 2008 , 4551-60, "The Inhalation Anaesthetic Isoflurane Induces a Vicious Cycle of Apoptosis and Aβ Accumulation." , J. Neurosci. , 27 , 2007 , 1247-1254
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